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WHEAT VARIETIES FROM 2BLADES, CSIRO, U OF MINNESOTA EXHIBIT EXCEPTIONAL STEM RUST RESISTANCE
Source: CSIRO, 2Blades and University of Minnesota joint news release

The stem rust susceptible wheat variety Fielder (left) in comparison to a derived Fielder line (right) with a five-gene stack of resistance genes.
Working with collaborators at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) and the University of Minnesota (UMN), 2Blades has demonstrated strong field resistance to stem rust disease in wheat containing a stack of five resistance genes.

Wheat stem rust is one of the world's most devastating plant diseases and is best controlled through the use of resistant varieties. The stem rust resistance of wheats grown widely today was achieved by conventional breeding dating back to the Green Revolution of the 1960s.

However, recently evolved strains of the stem rust pathogen can attack these wheats and threaten harvests again. Since 2008, 2Blades has led an international wheat rust consortium with the aim of fighting wheat stem and stripe rusts by sourcing and combining resistance genes from wheat and its relatives.

Dr. Mick Ayliffe's group at CSIRO in Australia has developed wheat lines carrying a 'cassette' of five or more individual genes for stem rust resistance. Some of these lines were tested in the field for the first time this past summer by Prof. Brian Steffenson at UMN and showed very strong resistance to stem rust. This result is especially significant because the combination of multiple independent resistance genes greatly reduces the chance of the pathogen evolving to overcome resistance.

"In my 30 years of conducting stem rust experiments in the field, I have never seen a clearer demonstration of the effectiveness of host resistance against this devastating disease - conferred in this case by a five-gene cassette of resistance genes transferred by genetic engineering", said Prof. Brian Steffenson, at the University of Minnesota.

Prof. Steve Swain, a Research Director at CSIRO, said "This is an exciting development toward producing crops with durable resistance to disease, which will contribute to sustainable food production and world food security."

Further experiments will assess the resistance of these lines against a diverse collection of pathogen strains, and possible effects of resistance gene cassettes on plant growth and vigor. 2Blades and collaborators are also working to develop additional wheat lines with new resistance combinations and to mount field trials in Sub-Saharan Africa and elsewhere.


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